Identification of a PadR-type regulator essential for intracellular pathogenesis of Burkholderia pseudomallei

Abstract Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a disease endemic to the tropics. Melioidosis manifests in various ways ranging from acute skin lesions to pneumonia and, in rare cases, infection of the central nervous system. Bp is a facultative intracellular pathogen...

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Bibliographic Details
Main Authors: Ian A. McMillan, Michael H. Norris, Jan Zarzycki-Siek, Yun Heacock-Kang, Zhenxin Sun, Bradley R. Borlee, Tung T. Hoang
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89852-7