Clonal anergy of CD117+chB6+ B cell progenitors induced by avian leukosis virus subgroup J is associated with immunological tolerance

Clonal anergy of CD117+chB6+ B cell progenitors induced by avian leukosis virus subgroup J is associated with immunological tolerance

Abstract Background The pathogenesis of immunological tolerance caused by avian leukosis virus subgroup J (ALV-J), an oncogenic retrovirus, is largely unknown. Results In this study, the development, differentiation, and immunological capability of B cells and their progenitors infected with ALV-J w...

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Bibliographic Details
Main Authors: Shuhai He, Gaoying Zheng, Defang Zhou, Gen Li, Mingjun Zhu, Xusheng Du, Jing Zhou, Ziqiang Cheng
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Retrovirology
Subjects:
Avian leukosis virus subgroup J
B cell progenitor
B cell anergy
Immunological tolerance
Congenital infection
Online Access:http://link.springer.com/article/10.1186/s12977-018-0463-9

Internet

http://link.springer.com/article/10.1186/s12977-018-0463-9

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