Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India

Background: Tubercular lymphadenitis (TBLN) remains the most frequent manifestation for extrapulmonary TB despite advancements in diagnostics and management over the years. Our study intends to explore five-year trend of TBLN in a tertiary care centre from south India, and aims to study clinico-demo...

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Main Authors: Akshita Gupta, Supriya Kunder, Druti Hazra, Vishnu Prasad Shenoy, Kiran Chawla
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:International Journal of Mycobacteriology
Subjects:
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2021;volume=10;issue=2;spage=162;epage=165;aulast=Gupta
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spelling doaj-7aba63da6740421981eda53138790ef72021-07-07T13:14:10ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2021-01-0110216216510.4103/ijmy.ijmy_66_21Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South IndiaAkshita GuptaSupriya KunderDruti HazraVishnu Prasad ShenoyKiran ChawlaBackground: Tubercular lymphadenitis (TBLN) remains the most frequent manifestation for extrapulmonary TB despite advancements in diagnostics and management over the years. Our study intends to explore five-year trend of TBLN in a tertiary care centre from south India, and aims to study clinico-demographic and diagnostic factors in the management of TBLN. Methods: All the adult patients (≥18 years) diagnosed and confirmed for TB lymphadenitis between January 2015 to December 2019 were retrospectively evaluated. Demographic factors, clinical manifestations, and different diagnostic approaches used in the management of TBLN were analysed using SPSS ver. 16. Results: A total of 164 patients with confirmed TBLN were included. Patients aged 18-45 years were the most affected (63.41%) with female dominancy. The most affected lymph nodes were cervical lymph nodes (84.1%) presenting with single palpable enlarged lymph node (80.5%). Majority (78.7%) of the lymph nodes were non-matted and 68.9% of enlarged lymph nodes were >3cm size. Excisional biopsy was performed for the majority of the patients 99 (60.4%) and 60.4% of the cases were managed with a combination of surgical excision and anti-tubercular treatment (ATT). Conclusions: The declining trend of TBLN observed in this study highlights the outcome of good public health policies; however, young females and high-risk groups like HIV infected or AIDS (affected more in the study) demand further attention. Overall, the advanced diagnostic tools along with surgical management and ATT can lead us to earlier diagnosis and successful treatment outcomeshttp://www.ijmyco.org/article.asp?issn=2212-5531;year=2021;volume=10;issue=2;spage=162;epage=165;aulast=Guptaextrapulmonary tuberculosisgenexpert mycobacterium tuberculosis/rifkarnatakalymph nodestubercular lymphadenitis
collection DOAJ
language English
format Article
sources DOAJ
author Akshita Gupta
Supriya Kunder
Druti Hazra
Vishnu Prasad Shenoy
Kiran Chawla
spellingShingle Akshita Gupta
Supriya Kunder
Druti Hazra
Vishnu Prasad Shenoy
Kiran Chawla
Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India
International Journal of Mycobacteriology
extrapulmonary tuberculosis
genexpert mycobacterium tuberculosis/rif
karnataka
lymph nodes
tubercular lymphadenitis
author_facet Akshita Gupta
Supriya Kunder
Druti Hazra
Vishnu Prasad Shenoy
Kiran Chawla
author_sort Akshita Gupta
title Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India
title_short Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India
title_full Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India
title_fullStr Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India
title_full_unstemmed Tubercular lymphadenitis in the 21st century: A 5-Year single-center retrospective study from South India
title_sort tubercular lymphadenitis in the 21st century: a 5-year single-center retrospective study from south india
publisher Wolters Kluwer Medknow Publications
series International Journal of Mycobacteriology
issn 2212-5531
2212-554X
publishDate 2021-01-01
description Background: Tubercular lymphadenitis (TBLN) remains the most frequent manifestation for extrapulmonary TB despite advancements in diagnostics and management over the years. Our study intends to explore five-year trend of TBLN in a tertiary care centre from south India, and aims to study clinico-demographic and diagnostic factors in the management of TBLN. Methods: All the adult patients (≥18 years) diagnosed and confirmed for TB lymphadenitis between January 2015 to December 2019 were retrospectively evaluated. Demographic factors, clinical manifestations, and different diagnostic approaches used in the management of TBLN were analysed using SPSS ver. 16. Results: A total of 164 patients with confirmed TBLN were included. Patients aged 18-45 years were the most affected (63.41%) with female dominancy. The most affected lymph nodes were cervical lymph nodes (84.1%) presenting with single palpable enlarged lymph node (80.5%). Majority (78.7%) of the lymph nodes were non-matted and 68.9% of enlarged lymph nodes were >3cm size. Excisional biopsy was performed for the majority of the patients 99 (60.4%) and 60.4% of the cases were managed with a combination of surgical excision and anti-tubercular treatment (ATT). Conclusions: The declining trend of TBLN observed in this study highlights the outcome of good public health policies; however, young females and high-risk groups like HIV infected or AIDS (affected more in the study) demand further attention. Overall, the advanced diagnostic tools along with surgical management and ATT can lead us to earlier diagnosis and successful treatment outcomes
topic extrapulmonary tuberculosis
genexpert mycobacterium tuberculosis/rif
karnataka
lymph nodes
tubercular lymphadenitis
url http://www.ijmyco.org/article.asp?issn=2212-5531;year=2021;volume=10;issue=2;spage=162;epage=165;aulast=Gupta
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