Hyperinflammation in Two Severe Acute Respiratory Syndrome Coronavirus 2-Infected Adolescents Successfully Treated With the Interleukin-1 Inhibitor Anakinra and Glucocorticoids

Hyperinflammation in Two Severe Acute Respiratory Syndrome Coronavirus 2-Infected Adolescents Successfully Treated With the Interleukin-1 Inhibitor Anakinra and Glucocorticoids

Background: In severe acute respiratory syndrome-related coronavirus (SARS-CoV-2) critically ill adults, hyperinflammation plays a key role in disease progression. The clinical manifestations of SARS-CoV-2 infection among children are much less severe compared with adult patients and usually associa...

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Bibliographic Details
Main Authors: Francesca I. Calò Carducci, Maria Antonietta De Ioris, Chiara Agrati, Rita Carsetti, Daniela Perrotta, Patrizia D'Argenio, Fabrizio De Benedetti, Stefania Notari, Paolo Rossi, Andrea Campana
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pediatrics
Subjects:
pediatric
coronavirus disease 2019
MIS-C
PIMS-TS
cytokine storm
anti-inflammatory treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2020.576912/full

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https://www.frontiersin.org/articles/10.3389/fped.2020.576912/full

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