Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution.

Imprinted genes are expressed in a parent-of-origin manner and are located in clusters throughout the genome. Aberrations in the expression of imprinted genes on human Chromosome 7 have been suggested to play a role in the etiologies of Russell-Silver Syndrome and autism. We describe the imprinting...

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Bibliographic Details
Main Authors: Layla Parker-Katiraee, Andrew R Carson, Takahiro Yamada, Philippe Arnaud, Robert Feil, Sayeda N Abu-Amero, Gudrun E Moore, Masahiro Kaneda, George H Perry, Anne C Stone, Charles Lee, Makiko Meguro-Horike, Hiroyuki Sasaki, Keiko Kobayashi, Kazuhiko Nakabayashi, Stephen W Scherer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1865561?pdf=render