One-Step Fabrication of Bone Morphogenetic Protein-2 Gene-Activated Porous Poly-L-Lactide Scaffold for Bone Induction

One-Step Fabrication of Bone Morphogenetic Protein-2 Gene-Activated Porous Poly-L-Lactide Scaffold for Bone Induction

Bone morphogenetic protein 2 (BMP2) is an efficacious inducer for the osteogenesis of mesenchymal stem cells (MSCs). Conventional applications of BMP2 have involved either the direct incorporation of BMP2 protein or ex vivo BMP2 gene transfer into stem cells prior to their transplantation. These app...

Full description

Bibliographic Details
Main Authors: Jingwen Xue, Hang Lin, Allison Bean, Ying Tang, Jian Tan, Rocky S. Tuan, Bing Wang
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
recombinant adeno-associated viral vector
bone morphogenetic protein-2 gene
mesenchymal stem cells
bone induction
gene therapy
ice porogen
gene-activated biomaterial scaffold
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050117300979

Internet

http://www.sciencedirect.com/science/article/pii/S2329050117300979

Similar Items