LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1.

LPS-Induced G-CSF Expression in Macrophages Is Mediated by ERK2, but Not ERK1.

Granulocyte colony-stimulating factor (G-CSF) selectively stimulates proliferation and differentiation of neutrophil progenitors which play important roles in host defense against infectious agents. However, persistent G-CSF production often leads to neutrophilia and excessive inflammatory reactions...

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Bibliographic Details
Main Authors: Shwu-Fen Chang, Shih-Shan Lin, Hui-Ching Yang, Yuan-Yi Chou, Jhen-I Gao, Shao-Chun Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4483241?pdf=render

Internet

http://europepmc.org/articles/PMC4483241?pdf=render

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