Poor Mobilization in T-Cell-Deficient Nude Mice is Explained by Defective Activation of Granulocytes and Monocytes

It has been reported that both SCID mice and SCID patients poorly mobilize hematopoietic stem/progenitor cells (HSPCs) in response to granulocyte colony-stimulating factor (G-CSF). This defect has been proposed to result from a lack of naturally occurring IgM immunoglobulins to trigger activation of...

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Bibliographic Details
Main Authors: Marcin Wysoczynski, Mateusz Adamiak, Malwina Suszynska, Ahmed Abdel-Latif, Janina Ratajczak, Mariusz Z. Ratajczak M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2017-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368916X692221