Towards practical biocatalytic Baeyer-Villiger reactions: applying a thermostable enzyme in the gram-scale synthesis of optically-active lactones in a two-liquid-phase system

Baeyer-Villiger monooxygenases (BVMOs) are extremely promising catalysts useful for enantioselective oxidation reactions of ketones, but organic chemists have not used them widely due to several reasons. These include instability of the enzymes in the case of in vitro and even in vivo systems, react...

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Bibliographic Details
Main Authors: Frank Schulz, François Leca, Frank Hollmann, Manfred T. Reetz
Format: Article
Language:English
Published: Beilstein-Institut 2005-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.1186/1860-5397-1-10