Magnetic targeting increases mesenchymal stromal cell retention in lungs and enhances beneficial effects on pulmonary damage in experimental silicosis

Magnetic targeting increases mesenchymal stromal cell retention in lungs and enhances beneficial effects on pulmonary damage in experimental silicosis

Abstract Silicosis is a pneumoconiosis caused by inhaled crystalline silica microparticles, which trigger inflammatory responses and granuloma formation in pulmonary parenchyma, thus affecting lung function. Although systemic administration of mesenchymal stromal cells (MSCs) ameliorates lung inflam...

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Bibliographic Details
Main Authors: Luisa H. A. Silva, Mariana C. Silva, Juliana B. Vieira, Emilia C. D. Lima, Renata C. Silva, Daniel J. Weiss, Marcelo M. Morales, Fernanda F. Cruz, Patricia R. M. Rocco
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Stem Cells Translational Medicine
Subjects:
magnetic fields
mesenchymal stem cells
nanoparticles
pulmonary fibrosis
silicosis
Online Access:https://doi.org/10.1002/sctm.20-0004

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