Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with Poor Prognosis and Chemoresistance in Lung Adenocarcinoma

Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with Poor Prognosis and Chemoresistance in Lung Adenocarcinoma

Background: The E3 ubiquitin ligase neural precursor cell expressed developmentally downregulated 4-1 (NEDD4-1) negatively regulates phosphatase and tensin homolog deleted on chromosome 10 (PTEN) protein levels through polyubiquitination and proteolysis, but its significance in lung cancer is still...

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Bibliographic Details
Main Authors: Ying-Hua Song, Cai-Qing Zhang, Fang-Fang Chen, Xiao-Yan Lin
Format: Article
Language:English
Published: Wolters Kluwer 2018-01-01
Series:Chinese Medical Journal
Subjects:
Chemoresistance; Lung Adenocarcinoma; NEDD4-1; PTEN 10; Prognosis
Online Access:http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=1;spage=16;epage=24;aulast=Song

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http://www.cmj.org/article.asp?issn=0366-6999;year=2018;volume=131;issue=1;spage=16;epage=24;aulast=Song

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