Lipocalin-2 may produce damaging effect after cerebral ischemia by inducing astrocytes classical activation

Lipocalin-2 may produce damaging effect after cerebral ischemia by inducing astrocytes classical activation

Abstract Background Functions of astrocytes in the rehabilitation after ischemic stroke, especially their impacts on inflammatory processes, remain controversial. This study uncovered two phenotypes of astrocytes, of which one was helpful, and the other harmful to anoxic neurons after brain ischemia...

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Bibliographic Details
Main Authors: Nan Zhao, Xiaomeng Xu, Yongjun Jiang, Jie Gao, Fang Wang, Xiaohui Xu, Zhuoyu Wen, Yi Xie, Juanji Li, Rongrong Li, Qiushi Lv, Qian Liu, Qiliang Dai, Xinfeng Liu, Gelin Xu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Neuroinflammation
Subjects:
Astrocytes
Functional polarization
LCN2
iNOS
Classical activation
Ischemic stroke
Online Access:http://link.springer.com/article/10.1186/s12974-019-1556-7

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http://link.springer.com/article/10.1186/s12974-019-1556-7

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