AICAR Sustains J1 Mouse Embryonic Stem Cell Self-Renewal and Pluripotency by Regulating Transcription Factor and Epigenetic Modulator Expression

AICAR Sustains J1 Mouse Embryonic Stem Cell Self-Renewal and Pluripotency by Regulating Transcription Factor and Epigenetic Modulator Expression

Backgroud/Aims: Embryonic stem cells (ES cells) have the capacity to propagate indefinitely, maintain pluripotency, and differentiate into any cell type under defined conditions. As a result, they are considered to be the best model system for research into early embryonic development. AICA ribonucl...

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Bibliographic Details
Main Authors: Xiaoyan Shi, Yongyan Wu, Zhiying Ai, Xin Liu, Liping Yang, Juan Du, Jingjing Shao, Zekun Guo, Yong Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Small molecule
Gene expression
Signal transduction
Epigenetic
Pluripotency
Online Access:http://www.karger.com/Article/FullText/354451

Internet

http://www.karger.com/Article/FullText/354451

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