Impaired reach-to-grasp kinematics in parkinsonian patients relates to dopamine-dependent, subthalamic beta bursts

Abstract Excessive beta-band oscillations in the subthalamic nucleus are key neural features of Parkinson’s disease. Yet the distinctive contributions of beta low and high bands, their dependency on striatal dopamine, and their correlates with movement kinematics are unclear. Here, we show that the...

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Bibliographic Details
Main Authors: Matteo Vissani, Chiara Palmisano, Jens Volkmann, Gianni Pezzoli, Silvestro Micera, Ioannis U. Isaias, Alberto Mazzoni
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00187-6