QTL mapping of rat blood pressure loci on RNO1 within a homologous region linked to human hypertension on HSA15.

Fine-mapping of regions linked to the inheritance of hypertension is accomplished by genetic dissection of blood pressure quantitative trait loci (BP QTLs) in rats. The goal of the current study was to further fine-map two genomic regions on rat chromosome 1 with opposing blood pressure effects (BP...

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Bibliographic Details
Main Authors: Blair Mell, Xi Cheng, Bina Joe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221658