Overexpression of Protein Tyrosine Phosphatase 1B in HepG2 Cells Ameliorates Insulin-mediated Suppression of Apolipoprotein B mRNA Translation Via Its Untranslated Regions

Overexpression of Protein Tyrosine Phosphatase 1B in HepG2 Cells Ameliorates Insulin-mediated Suppression of Apolipoprotein B mRNA Translation Via Its Untranslated Regions

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Background: The hepatic secretion of apolipoprotein B (apoB), containing lipoproteins, is known to be regulated by insulin, and the overproduction of these atherogenic lipoproteins occurs in insulin-resistant states. Protein tyrosine phosphatase 1B (PTP-1B) is a key regulator of hepatic insulin sign...

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Bibliographic Details
Main Authors: Parvin Pasalar, Wei Qiu, Rita Kohen Avramoglu, Gus Sidiropoulos, Khosrow Adeli
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2007-04-01
Series:Journal of Tehran University Heart Center
Subjects:
Protein tyrosine phosphatase 1B
Untranslated region
In vitro translation assay
Online Access:https://jthc.tums.ac.ir/index.php/jthc/article/view/47

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https://jthc.tums.ac.ir/index.php/jthc/article/view/47

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