Low-mutation-rate, reduced-genome <it>Escherichia coli</it>: an improved host for faithful maintenance of engineered genetic constructs

<p>Abstract</p> <p>Background</p> <p>Molecular mechanisms generating genetic variation provide the basis for evolution and long-term survival of a population in a changing environment. In stable, laboratory conditions, the variation-generating mechanisms are dispensable...

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Bibliographic Details
Main Authors: Csörgő Bálint, Fehér Tamás, Tímár Edit, Blattner Frederick R, Pósfai György
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://www.microbialcellfactories.com/content/11/1/11