Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial

Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial

Abstract Background This study assessed the safety and efficacy of intrathecal injection of umbilical cord tissue mesenchymal stem cells (UCT-MSC) in individuals with cerebral palsy (CP). The diffusion tensor imaging (DTI) was performed to evaluate the alterations in white-matter integrity. Methods...

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Bibliographic Details
Main Authors: Man Amanat, Anahita Majmaa, Morteza Zarrabi, Masoumeh Nouri, Masood Ghahvechi Akbari, Ali Reza Moaiedi, Omid Ghaemi, Fatemeh Zamani, Sharif Najafi, Reza Shervin Badv, Massoud Vosough, Amir Ali Hamidieh, Mona Salehi, Hadi Montazerlotfelahi, Ali Reza Tavasoli, Morteza Heidari, Hossein Mohebi, Ali Fatemi, Amir Garakani, Mahmoud Reza Ashrafi
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Cerebral palsy
Stem cell
Diffusion tensor imaging
Gross motor function
Children
Online Access:https://doi.org/10.1186/s13287-021-02513-4

Internet

https://doi.org/10.1186/s13287-021-02513-4

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