Vaccine-linked chemotherapy induces IL-17 production and reduces cardiac pathology during acute Trypanosoma cruzi infection

Abstract Chagas disease resulting from Trypanosoma cruzi infection leads to a silent, long-lasting chronic neglected tropical disease affecting the poorest and underserved populations around the world. Antiparasitic treatment with benznidazole does not prevent disease progression or death in patient...

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Bibliographic Details
Main Authors: Julio V. Cruz-Chan, Liliana E. Villanueva-Lizama, Leroy Versteeg, Ashish Damania, Maria José Villar, Cristina González-López, Brian Keegan, Jeroen Pollet, Fabian Gusovsky, Peter J. Hotez, Maria Elena Bottazzi, Kathryn M. Jones
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82930-w