AEBP1 expression increases with severity of fibrosis in NASH and is regulated by glucose, palmitate, and miR-372-3p.

Factors governing the development of liver fibrosis in nonalcoholic steatohepatitis (NASH) are only partially understood. We recently identified adipocyte enhancer binding protein 1 (AEBP1) as a member of a core set of dysregulated fibrosis-specific genes in human NASH. Here we sought to investigate...

Full description

Bibliographic Details
Main Authors: Glenn S Gerhard, Amanda Hanson, Danielle Wilhelmsen, Ignazio S Piras, Christopher D Still, Xin Chu, Anthony T Petrick, Johanna K DiStefano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0219764