Detection of oligoclonal IgG kappa and IgG lambda bands in cerebrospinal fluid and serum with Hevylite™ antibodies. comparison with the free light chain oligoclonal pattern

<p>Abstract</p> <p>Background</p> <p>Oligoclonal IgG bands in cerebrospinal fluid that are absent in serum indicate intrathecal IgG synthesis and are a sensitive marker of CNS inflammatory diseases, in particular multiple sclerosis. It may be of interest to determine wh...

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Bibliographic Details
Main Authors: Zeman David, Hradílek Pavel, Švagera Zdeněk, Mojžíšková Eva, Woznicová Ivana, Zapletalová Olga
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://www.fluidsbarrierscns.com/content/9/1/5