Does the Inhibitory Action of Asymmetric Dimethylarginine (ADMA) on the Endothelial Nitric Oxide Synthase Activity Explain Its Importance in the Cardiovascular System? The ADMA Paradox

Asymmetric dimethylarginine (ADMA, NG, NG-dimethyl-L-arginine) is endogenously produced by asymmetric dimethylation of the guanidine group of L-arginine residues. ADMA is generally considered a powerful cardiovascular risk factor, an Übermarker, due to its inhibitory action on the activity of nitric...

Full description

Bibliographic Details
Main Author: Dimitrios Tsikas
Format: Article
Language:English
Published: Biogenic Press 2017-07-01
Series:Journal of Controversies in Biomedical Research
Subjects:
Online Access:https://jcbmr.com/index.php/jcbmr/article/view/22