Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity.

Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity.

Structural diversity in the peptide binding sites of the redundant classical MHC antigen presenting molecules is strongly selected in humans and mice. Although the encoded antigen presenting molecules overlap in antigen presenting function, differences in polymorphism at the MHC I A, B and C loci in...

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Bibliographic Details
Main Authors: Kevin D Pavelko, Yanice Mendez-Fernandez, Michael P Bell, Michael J Hansen, Aaron J Johnson, Chella S David, Moses Rodriguez, Larry R Pease
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3285594?pdf=render

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http://europepmc.org/articles/PMC3285594?pdf=render

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