Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity.
Structural diversity in the peptide binding sites of the redundant classical MHC antigen presenting molecules is strongly selected in humans and mice. Although the encoded antigen presenting molecules overlap in antigen presenting function, differences in polymorphism at the MHC I A, B and C loci in...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-02-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC3285594?pdf=render |