Impact of FMR1 Premutation on Neurobehavior and Bioenergetics in Young Monozygotic Twins

Impact of FMR1 Premutation on Neurobehavior and Bioenergetics in Young Monozygotic Twins

Mitochondrial dysfunction (MD) has been identified in lymphocytes, fibroblasts and brain samples from adults carrying a 55–200 CGG expansion in the fragile X mental retardation 1 (FMR1) gene (premutation; PM); however, limited data are available on the bioenergetics of pediatric carriers. Here we di...

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Bibliographic Details
Main Authors: Eleonora Napoli, Andrea Schneider, Randi Hagerman, Gyu Song, Sarah Wong, Flora Tassone, Cecilia Giulivi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Genetics
Subjects:
bioenergetics
FXTAS
mitochondrial dysfunction
oxidative stress
premutation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00338/full

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