Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan
Abstract: Background: Healthcare workers (HCWs) can act as asymptomatic carrier in transmitting Methicillin Resistant Staphylococcus aureus (MRSA). Availability of epidemiological and antibiotic susceptibility data is necessary to limit the spread of HCWs-associated MRSA infections, and to help p...
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doaj-7ec03aaec7af4bc1a74138a6abe1dfc62021-02-01T08:54:55ZengAlexandria UniversityJournal of High Institute of Public Health2357-06012357-061X2013-06-0143111210.21608/JHIPH.2013.19984Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of JordanHamed M. Alzoubi0Amin A. Aqel1Munir Abu-Helalah2*Ph.D medical microbiology, Medical Microbiology and Immunology Department, Faculty of Medicine, Mu'tah University, Alkarak, Jordan *Ph.D medical microbiology, Medical Microbiology and Immunology Department, Faculty of Medicine, Mu'tah University, Alkarak, Jordan Ph.D preventive medicine, Department of Public Health, Faculty of Medicine, Mu'tah University, Alkarak, JordanAbstract: Background: Healthcare workers (HCWs) can act as asymptomatic carrier in transmitting Methicillin Resistant Staphylococcus aureus (MRSA). Availability of epidemiological and antibiotic susceptibility data is necessary to limit the spread of HCWs-associated MRSA infections, and to help physicians in choosing the appropriate empirical antibiotic for management of such infections. Objective: to assess nasal carriage and antibiogram of MRSA in healthcare workers from Southern Jordan. Methods: a total of 276 nasal swabs were randomly collected from the HCWs. MRSA was identified by culture, biochemical and molecular methods. Antibiotic susceptibility was determined by the disc diffusion method. Results: The HCWs-MRSA nasal carriage was 8.7%. There was significant difference for nasal carriage of MRSA by nurse occupation (p value = 0.007), education level of less than a university degree (p value = 0.039) and years of HCW experience (p value = 0.023). No significant difference by age, sex, antibiotic exposure or smoking. Antibiotic resistance to Trimethoprim-Sulfamethoxazole and Tetracycline was detected in 37.5% and 12.5% of all MRSA isolates respectively. No resistance to the other antibiotics used in this study and no multidrug resistance was encountered in all MRSA isolates. Conclusion: MRSA nasal carriage among HCWs in this study was 8.7% with no alarming antibiotic resistance pattern. Nurses, less educated and more experienced HCWs are at increased risk of MRSA nasal carriage. Therefore, we strongly recommend screening and decolonizing positive HCWs who can act as asymptomatic carriers in MRSA transmission cycle. methicillin resistant staphylococcus aureushealthcare workersantibiogram |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hamed M. Alzoubi Amin A. Aqel Munir Abu-Helalah |
spellingShingle |
Hamed M. Alzoubi Amin A. Aqel Munir Abu-Helalah Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan Journal of High Institute of Public Health methicillin resistant staphylococcus aureus healthcare workers antibiogram |
author_facet |
Hamed M. Alzoubi Amin A. Aqel Munir Abu-Helalah |
author_sort |
Hamed M. Alzoubi |
title |
Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan |
title_short |
Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan |
title_full |
Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan |
title_fullStr |
Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan |
title_full_unstemmed |
Prevalence of Methicillin Resistant Staphylococcus aureus Nasal Carriage and its Antibiogram in Healthcare Workers from South of Jordan |
title_sort |
prevalence of methicillin resistant staphylococcus aureus nasal carriage and its antibiogram in healthcare workers from south of jordan |
publisher |
Alexandria University |
series |
Journal of High Institute of Public Health |
issn |
2357-0601 2357-061X |
publishDate |
2013-06-01 |
description |
Abstract:
Background: Healthcare workers (HCWs) can act as asymptomatic carrier in transmitting Methicillin
Resistant Staphylococcus aureus (MRSA). Availability of epidemiological and antibiotic susceptibility
data is necessary to limit the spread of HCWs-associated MRSA infections, and to help physicians in
choosing the appropriate empirical antibiotic for management of such infections. Objective: to
assess nasal carriage and antibiogram of MRSA in healthcare workers from Southern Jordan.
Methods: a total of 276 nasal swabs were randomly collected from the HCWs. MRSA was identified
by culture, biochemical and molecular methods. Antibiotic susceptibility was determined by the disc
diffusion method. Results: The HCWs-MRSA nasal carriage was 8.7%. There was significant
difference for nasal carriage of MRSA by nurse occupation (p value = 0.007), education level of less
than a university degree (p value = 0.039) and years of HCW experience (p value = 0.023). No
significant difference by age, sex, antibiotic exposure or smoking. Antibiotic resistance to
Trimethoprim-Sulfamethoxazole and Tetracycline was detected in 37.5% and 12.5% of all MRSA
isolates respectively. No resistance to the other antibiotics used in this study and no multidrug
resistance was encountered in all MRSA isolates. Conclusion: MRSA nasal carriage among HCWs
in this study was 8.7% with no alarming antibiotic resistance pattern. Nurses, less educated and
more experienced HCWs are at increased risk of MRSA nasal carriage. Therefore, we strongly
recommend screening and decolonizing positive HCWs who can act as asymptomatic carriers in
MRSA transmission cycle. |
topic |
methicillin resistant staphylococcus aureus healthcare workers antibiogram |
work_keys_str_mv |
AT hamedmalzoubi prevalenceofmethicillinresistantstaphylococcusaureusnasalcarriageanditsantibiograminhealthcareworkersfromsouthofjordan AT aminaaqel prevalenceofmethicillinresistantstaphylococcusaureusnasalcarriageanditsantibiograminhealthcareworkersfromsouthofjordan AT munirabuhelalah prevalenceofmethicillinresistantstaphylococcusaureusnasalcarriageanditsantibiograminhealthcareworkersfromsouthofjordan |
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