HSP70 Promoter-Driven Activation of Gene Expression for Immunotherapy Using Gold Nanorods and Near Infrared Light

Modulation of the cytokine milieu is one approach for vaccine development. However, therapy with pro-inflammatory cytokines, such as IL-12, is limited in practice due to adverse systemic effects. Spatially-restricted gene expression circumvents this problem by enabling localized amplification. Intra...

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Bibliographic Details
Main Authors: Helen A. Andersson, Yoo-Shin Kim, Brian E. O'Neill, Zheng-Zheng Shi, Rita E. Serda
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Vaccines
Subjects:
Online Access:http://www.mdpi.com/2076-393X/2/2/216