Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis.

Atherosclerosis, the predominant cause of death in well-resourced countries, may develop in the presence of plasma lipid levels within the normal range. Inflammation may contribute to lesion development in these individuals, but the underlying mechanisms are not well understood. Transgenic mice expr...

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Bibliographic Details
Main Authors: Mohamed Higazi, Suhair Abdeen, Rami Abu-Fanne, Samuel N Heyman, Aseel Masarwy, Khalil Bdeir, Emad Maraga, Douglas B Cines, Abd Al-Roof Higazi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231582