A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

A novel sustained‐release cysteamine bitartrate formulation for the treatment of cystinosis: Pharmacokinetics and safety in healthy male volunteers

Abstract The strict intake regimen of cysteamine bitartrate formulations, associated with side effects, is a concern for the treatment compliance in cystinosis therapy. Therefore, there is a need for a cysteamine formulation with an improved pharmacokinetic profile. This study investigated the pharm...

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Bibliographic Details
Main Authors: Cécile L. Berends, Lisa Pagan, Michiel J. vanEsdonk, Naomi B. Klarenbeek, Kirsten R. Bergmann, Matthijs Moerland, Vincent van derWel, Saco J. deVisser, Hans Büller, Frans deLoos, Wouter S. deVries, Hans Waals, Leo G. J. deLeede, Jacobus Burggraaf, Ingrid M. C. Kamerling
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Pharmacology Research & Perspectives
Subjects:
compliance
cystagon
cysteamine
cystinosis
sustained‐release
Online Access:https://doi.org/10.1002/prp2.739

Internet

https://doi.org/10.1002/prp2.739

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