Peroxisome Proliferator-Activated Receptor Alpha Mediates the Beneficial Effects of Atorvastatin in Experimental Colitis

Peroxisome Proliferator-Activated Receptor Alpha Mediates the Beneficial Effects of Atorvastatin in Experimental Colitis

The current therapeutic options for Inflammatory Bowel Diseases (IBD) are limited. Even using common anti-inflammatory, immunosuppressive or biological therapies, many patients become unresponsive to the treatments, immunosuppressed or unable to restrain secondary infections. Statins are cholesterol...

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Bibliographic Details
Main Authors: Paulo José Basso, Helioswilton Sales-Campos, Viviani Nardini, Murillo Duarte-Silva, Vanessa Beatriz Freitas Alves, Giuliano Bonfá, Cassiano Costa Rodrigues, Bruno Ghirotto, Javier Emílio Lazo Chica, Auro Nomizo, Cristina Ribeiro de Barros Cardoso
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
Inflammatory bowel diseases
ulcerative colitis
crohn’s disease
therapy
statins
dextran sodium sulfate
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.618365/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.618365/full

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