The association between areas of secondary hyperalgesia and volumes of the caudate nuclei and other pain relevant brain structures-A 3-tesla MRI study of healthy men.

INTRODUCTION:Central sensitization plays a pivotal role in maintenance of pain and is believed to be intricately involved in several chronic pain conditions. One clinical manifestation of central sensitization is secondary hyperalgesia. The degree of secondary hyperalgesia presumably reflects indivi...

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Main Authors: Morten S Hansen, Mohammad S Asghar, Jørn Wetterslev, Christian B Pipper, Johan Mårtensson, Lino Becerra, Anders Christensen, Janus D Nybing, Inger Havsteen, Mikael Boesen, Jørgen B Dahl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6103511?pdf=render