Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS

Summary: Spinal motor axons traverse large distances to innervate target muscles, thus requiring local control of cellular events for proper functioning. To interrogate axon-specific processes we developed Axon-seq, a refined method incorporating microfluidics, RNA sequencing (RNA-seq), and bioinfor...

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Bibliographic Details
Main Authors: Jik Nijssen, Julio Aguila, Rein Hoogstraaten, Nigel Kee, Eva Hedlund
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118304739