Clinical, biological and genetic analysis of prepubertal isolated ovarian cyst in 11 girls.

<h4>Background</h4>The cause of isolated gonadotropin-independent precocious puberty (PP) with an ovarian cyst is unknown in the majority of cases. Here, we describe 11 new cases of peripheral PP and, based on phenotypes observed in mouse models, we tested the hypothesis that mutations i...

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Bibliographic Details
Main Authors: Raja Brauner, Anu Bashamboo, Sébastien Rouget, Marie Goulet, Pascal Philibert, Hélène Sarda-Thibault, Christine Trivin, Micheline Misrahi, Charles Sultan, Ken McElreavey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20593028/?tool=EBI