Regulation of DNA Repair Mechanisms: How the Chromatin Environment Regulates the DNA Damage Response

Cellular DNA is constantly challenged by damage-inducing factors derived from exogenous or endogenous sources. In order to maintain genome stability and integrity, cells have evolved a wide variety of DNA repair pathways which counteract different types of DNA lesions, also referred to as the DNA da...

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Bibliographic Details
Main Authors: Jens Stadler, Holger Richly
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/18/8/1715