Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin.

Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin.

Fragile X mental Retardation Protein (FMRP) is a well-known regulator of local translation of its mRNA targets in neurons. However, despite its ubiquitous expression, the role of FMRP remains ill-defined in other cell types. In this study we investigated the subcellular distribution of FMRP and its...

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Bibliographic Details
Main Authors: Mohamed S Taha, Kazem Nouri, Lech G Milroy, Jens M Moll, Christian Herrmann, Luc Brunsveld, Roland P Piekorz, Mohammad R Ahmadian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3962360?pdf=render

Internet

http://europepmc.org/articles/PMC3962360?pdf=render

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