The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo

The PDZ-Binding Motif of HPV16-E6 Oncoprotein Modulates the Keratinization and Stemness Transcriptional Profile In Vivo

Objective. The aim of this work was to compare the early gene expression profiles in the skin of HPV16-E6 transgenic mice regulated by the E6 PDZ-binding motif. Materials and Methods. The global transcriptional profiles in dorsal skin biopsies from K14E6 and K14E6Δ146-151 transgenic mice were compar...

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Bibliographic Details
Main Authors: Enoc Mariano Cortés-Malagón, Carmen Palacios-Reyes, Sandra Romero-Cordoba, Daniel Mendoza-Villanueva, Jaime Escobar-Herrera, Odette Verdejo-Torres, Rubén Gerardo Contreras, Gloria Fernádez-Tilapa, Mario Adan Moreno-Eutimio, José Moreno, Alfredo Hidalgo-Miranda, Patricio Gariglio, José Bonilla-Delgado
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2017/7868645

Internet

http://dx.doi.org/10.1155/2017/7868645

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