A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer.

Colorectal cancer is one of the most common cancers in developed nations and is the result of both environmental and genetic factors. Many of the genetic lesions observed in colorectal cancer alter expression of homeobox genes, which encode homeodomain transcription factors. The MEIS1 homeobox gene...

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Bibliographic Details
Main Authors: Richard C Crist, Jacquelyn J Roth, Scott A Waldman, Arthur M Buchberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3157405?pdf=render