Assessing the Functional Heterogeneity of Monocytes in Human Septic Shock: a Proof-of-Concept Microfluidic Assay of TNFα Secretion

Assessing the Functional Heterogeneity of Monocytes in Human Septic Shock: a Proof-of-Concept Microfluidic Assay of TNFα Secretion

ObjectiveThe development of advanced single-cell technologies to decipher inter-cellular heterogeneity has enabled the dynamic assessment of individual cells behavior over time, overcoming the limitation of traditional assays. Here, we evaluated the feasibility of an advanced microfluidic assay comb...

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Bibliographic Details
Main Authors: Jean-François Llitjos, Yacine Bounab, Christophe Rousseau, Sophie Dixneuf, Blandine Rimbault, Jean-Daniel Chiche, Julien Textoris, Frédéric Pène, Christophe Védrine
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
septic shock
immune suppression
monocyte
microfluidic
tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.686111/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.686111/full

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