Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality
Objectives: Necrotizing fasciitis (NF) is rare but life threatening soft tissue infection characterized by a necrotizing process of the subcutaneous tissues and fascial planes. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been verified as a useful diagnostic tool for de...
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Wolters Kluwer Medknow Publications
2014-03-01
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doaj-80c522ab62004e32ad47647a431ce4802021-02-02T06:45:58ZengWolters Kluwer Medknow PublicationsTurkish Journal of Emergency Medicine2452-24732014-03-01141151910.5505/1304.7361.2014.55476Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with MortalityElif COLAKNuraydin OZLEMGultekin Ozan KUCUKRecep AKTIMURSadik KESMERObjectives: Necrotizing fasciitis (NF) is rare but life threatening soft tissue infection characterized by a necrotizing process of the subcutaneous tissues and fascial planes. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been verified as a useful diagnostic tool for detecting necrotizing fasciitis. A certain LRINEC score might also be associated with mortality. The aims of this study are to determine risk factors affecting the prognosis and to evaluate the prognostic value of the LRINEC score in NF. Methods: Twenty-five patients with necrotizing fasciitis treated in Samsun Education and Research Hospital between January 2008 and April 2013 were enrolled in the study. Surviving and non-surviving patient groups were compared regarding demographic data, co-morbidity, predisposing factors, causative agents, number of debridements and LRINEC score. Results: Mean age was 55.6±16.79 years (min: 17-max: 84), and the female/male ratio was 16/9. Mortality was observed in 6 (24%) patients. The most frequent comorbid diseases were diabetes mellitus (52) and peripheral circulatory disorders (24%), and the most frequent etiologies were cutaneous (32%) and perianal abscess (20%). Pseudomonas aeruginosa infection was higher in the non-surviving group (p=0.006). The mean number of debridements and LRINEC score were higher in the non-surviving group than in the surviving group (p=0.003 and p=0.003, respectively). Conclusions: Pseudomans aeruginosa infection and multiple debridements are related with mortality. The LRINEC score might help predict mortality in NF.http://www.sciencedirect.com/science/article/pii/S2452247316300346Fasciitismortalitynecrotizingprognosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Elif COLAK Nuraydin OZLEM Gultekin Ozan KUCUK Recep AKTIMUR Sadik KESMER |
spellingShingle |
Elif COLAK Nuraydin OZLEM Gultekin Ozan KUCUK Recep AKTIMUR Sadik KESMER Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality Turkish Journal of Emergency Medicine Fasciitis mortality necrotizing prognosis |
author_facet |
Elif COLAK Nuraydin OZLEM Gultekin Ozan KUCUK Recep AKTIMUR Sadik KESMER |
author_sort |
Elif COLAK |
title |
Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality |
title_short |
Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality |
title_full |
Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality |
title_fullStr |
Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality |
title_full_unstemmed |
Laboratory Risk Indicators for Necrotizing Fasciitis and Associations with Mortality |
title_sort |
laboratory risk indicators for necrotizing fasciitis and associations with mortality |
publisher |
Wolters Kluwer Medknow Publications |
series |
Turkish Journal of Emergency Medicine |
issn |
2452-2473 |
publishDate |
2014-03-01 |
description |
Objectives: Necrotizing fasciitis (NF) is rare but life threatening soft tissue infection characterized by a necrotizing process of the subcutaneous tissues and fascial planes. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score has been verified as a useful diagnostic tool for detecting necrotizing fasciitis. A certain LRINEC score might also be associated with mortality. The aims of this study are to determine risk factors affecting the prognosis and to evaluate the prognostic value of the LRINEC score in NF.
Methods: Twenty-five patients with necrotizing fasciitis treated in Samsun Education and Research Hospital between January 2008 and April 2013 were enrolled in the study. Surviving and non-surviving patient groups were compared regarding demographic data, co-morbidity, predisposing factors, causative agents, number of debridements and LRINEC score.
Results: Mean age was 55.6±16.79 years (min: 17-max: 84), and the female/male ratio was 16/9. Mortality was observed in 6 (24%) patients. The most frequent comorbid diseases were diabetes mellitus (52) and peripheral circulatory disorders (24%), and the most frequent etiologies were cutaneous (32%) and perianal abscess (20%). Pseudomonas aeruginosa infection was higher in the non-surviving group (p=0.006). The mean number of debridements and LRINEC score were higher in the non-surviving group than in the surviving group (p=0.003 and p=0.003, respectively).
Conclusions: Pseudomans aeruginosa infection and multiple debridements are related with mortality. The LRINEC score might help predict mortality in NF. |
topic |
Fasciitis mortality necrotizing prognosis |
url |
http://www.sciencedirect.com/science/article/pii/S2452247316300346 |
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