Non-human primate and rodent embryonic stem cells are differentially sensitive to embryotoxic compounds

Many industrial chemicals and their respective by-products need to be comprehensively evaluated for toxicity using reliable and efficient assays. In terms of teratogenicity evaluations, the murine-based embryonic stem cell test (EST) offers a promising solution to screen for multiple tissue endpoint...

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Bibliographic Details
Main Authors: Lauren Walker, Laura Baumgartner, Kevin C. Keller, Julia Ast, Susanne Trettner, Nicole I. zur Nieden
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014001516