Alteration of Mevalonate Pathway in Proliferated Vascular Smooth Muscle from Diabetic Mice: Possible Role in High-Glucose-Induced Atherogenic Process

The proliferation of vascular smooth muscle cells (VSMCs) is one of the main features of atherosclerosis induced by high glucose. Mevalonate pathway is an important metabolic pathway that plays a key role in multiple cellular processes. The aim of this study was to define whether the enzyme expressi...

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Bibliographic Details
Main Authors: Guo-Ping Chen, Xiao-Qin Zhang, Tao Wu, Liang Li, Jie Han, Chang-Qing Du
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2015/379287