Inhibition of Streptococcus mutans polysaccharide synthesis by molecules targeting glycosyltransferase activity

Glycosyltransferase (Gtf) is one of the crucial virulence factors of Streptococcus mutans, a major etiological pathogen of dental caries. All the available evidence indicates that extracellular polysaccharide, particularly glucans produced by S. mutans Gtfs, contribute to the cariogenicity of dental...

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Bibliographic Details
Main Authors: Zhi Ren, Lulu Chen, Jiyao Li, Yuqing Li
Format: Article
Published: Taylor & Francis Group 2016-04-01
Series:Journal of Oral Microbiology
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