Analysis of the Immune Responses in the Ileum of Gnotobiotic Pigs Infected with the Recombinant GII.p12_GII.3 Human Norovirus by mRNA Sequencing

Analysis of the Immune Responses in the Ileum of Gnotobiotic Pigs Infected with the Recombinant GII.p12_GII.3 Human Norovirus by mRNA Sequencing

Norovirus genogroup II (NoV GII) induces acute gastrointestinal food-borne illness in humans. Because gnotobiotic pigs can be infected with human norovirus (HuNoV) GII, they are frequently used to analyze the associated pathogenic mechanisms and immune responses, which remain poorly understood. Rece...

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Bibliographic Details
Main Authors: Byung-Joo Park, Hee-Seop Ahn, Sang-Hoon Han, Hyeon-Jeong Go, Dong-Hwi Kim, Changsun Choi, Soontag Jung, Jinjong Myoung, Joong-Bok Lee, Seung-Yong Park, Chang-Seon Song, Sang-Won Lee, Hoon-Taek Lee, In-Soo Choi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
human norovirus
gnotobiotic pig
immune response
high-throughput mRNA sequencing
Online Access:https://www.mdpi.com/1999-4915/13/1/92

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https://www.mdpi.com/1999-4915/13/1/92

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