Dynamics of high viscosity contrast confluent microfluidic flows

Abstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large vi...

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Main Authors: Michael E. Kurdzinski, Berrak Gol, Aaron Co Hee, Peter Thurgood, Jiu Yang Zhu, Phred Petersen, Arnan Mitchell, Khashayar Khoshmanesh
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-06260-6
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spelling doaj-81f8c0f6d1034825bd243d5b9158e4892020-12-08T00:50:14ZengNature Publishing GroupScientific Reports2045-23222017-07-017111110.1038/s41598-017-06260-6Dynamics of high viscosity contrast confluent microfluidic flowsMichael E. Kurdzinski0Berrak Gol1Aaron Co Hee2Peter Thurgood3Jiu Yang Zhu4Phred Petersen5Arnan Mitchell6Khashayar Khoshmanesh7School of Engineering, RMIT UniversitySchool of Engineering, RMIT UniversitySchool of Engineering, RMIT UniversitySchool of Engineering, RMIT UniversitySchool of Engineering, RMIT UniversitySchool of Media and Communication, RMIT UniversitySchool of Engineering, RMIT UniversitySchool of Engineering, RMIT UniversityAbstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large viscosity contrast between the neighbouring flows leading to unique instability patterns along their interface. Here, we study the dynamics of high viscosity contrast confluent flows – specifically a core flow made of highly viscous glycerol confined by sheath flows made of water within a microfluidic flow focusing system. Our experiments indicate the formation of tapered core structures along the middle of the channel. Increasing the sheath flow rate shortens the tapered core, and importantly induces local instability patterns along the interface of core-sheath flows. The dynamics of such tapered core structures is governed by the intensity of instability patterns and the length of the core, according to which the core structure can experience stable, disturbed, broken or oscillated regimes. We have studied the dynamics of tapered core structures under these regimes. In particular, we have analysed the amplitude and frequency of core displacements during the broken core and oscillating core regimes, which have not been investigated before.https://doi.org/10.1038/s41598-017-06260-6
collection DOAJ
language English
format Article
sources DOAJ
author Michael E. Kurdzinski
Berrak Gol
Aaron Co Hee
Peter Thurgood
Jiu Yang Zhu
Phred Petersen
Arnan Mitchell
Khashayar Khoshmanesh
spellingShingle Michael E. Kurdzinski
Berrak Gol
Aaron Co Hee
Peter Thurgood
Jiu Yang Zhu
Phred Petersen
Arnan Mitchell
Khashayar Khoshmanesh
Dynamics of high viscosity contrast confluent microfluidic flows
Scientific Reports
author_facet Michael E. Kurdzinski
Berrak Gol
Aaron Co Hee
Peter Thurgood
Jiu Yang Zhu
Phred Petersen
Arnan Mitchell
Khashayar Khoshmanesh
author_sort Michael E. Kurdzinski
title Dynamics of high viscosity contrast confluent microfluidic flows
title_short Dynamics of high viscosity contrast confluent microfluidic flows
title_full Dynamics of high viscosity contrast confluent microfluidic flows
title_fullStr Dynamics of high viscosity contrast confluent microfluidic flows
title_full_unstemmed Dynamics of high viscosity contrast confluent microfluidic flows
title_sort dynamics of high viscosity contrast confluent microfluidic flows
publisher Nature Publishing Group
series Scientific Reports
issn 2045-2322
publishDate 2017-07-01
description Abstract The laminar nature of microfluidic flows is most elegantly demonstrated via the confluence of two fluids forming two stable parallel flows within a single channel meeting at a highly stable interface. However, maintenance of laminar conditions can become complicated when there is a large viscosity contrast between the neighbouring flows leading to unique instability patterns along their interface. Here, we study the dynamics of high viscosity contrast confluent flows – specifically a core flow made of highly viscous glycerol confined by sheath flows made of water within a microfluidic flow focusing system. Our experiments indicate the formation of tapered core structures along the middle of the channel. Increasing the sheath flow rate shortens the tapered core, and importantly induces local instability patterns along the interface of core-sheath flows. The dynamics of such tapered core structures is governed by the intensity of instability patterns and the length of the core, according to which the core structure can experience stable, disturbed, broken or oscillated regimes. We have studied the dynamics of tapered core structures under these regimes. In particular, we have analysed the amplitude and frequency of core displacements during the broken core and oscillating core regimes, which have not been investigated before.
url https://doi.org/10.1038/s41598-017-06260-6
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