Annexin I and dexamethasone effects on phospholipase and cyclooxygenase activity in human synoviocytes

Annexin I is a glucocorticoid-induced mediator with anti-inflammatory activity in animal models of arthritis. We studied the effects of a bioactive annexin I peptide, ac 2–26, dexamethasone (DEX), and interleukin-1β (IL-1β) on phospholipase A2 (PLA2) and cyclooxygenase (COX) activities and prostagl...

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Bibliographic Details
Main Authors: Annaleise V. Sampey, Paul Hutchinson, Eric F. Morand
Format: Article
Language:English
Published: Hindawi Limited 2000-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350020018357