Vertebrate Left-Right Asymmetry: What Can Nodal Cascade Gene Expression Patterns Tell Us?

Laterality of inner organs is a wide-spread characteristic of vertebrates and beyond. It is ultimately controlled by the left-asymmetric activation of the Nodal signaling cascade in the lateral plate mesoderm of the neurula stage embryo, which results from a cilia-driven leftward flow of extracellul...

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Bibliographic Details
Main Authors: Axel Schweickert, Tim Ott, Sabrina Kurz, Melanie Tingler, Markus Maerker, Franziska Fuhl, Martin Blum
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/5/1/1