Detection of low frequency multi-drug resistance and novel putative maribavir resistance in immunocompromised paediatric patients with cytomegalovirus

Detection of low frequency multi-drug resistance and novel putative maribavir resistance in immunocompromised paediatric patients with cytomegalovirus

Human cytomegalovirus (HCMV) is a significant pathogen in immunocompromised individuals, with the potential to cause fatal pneumonitis and colitis, as well as increasing the risk of organ rejection in transplant patients. With the advent of new anti-HCMV drugs there is therefore considerable interes...

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Bibliographic Details
Main Authors: Charlotte Jane Houldcroft, Josephine M Bryant, Daniel P Depledge, Ben K Margetts, Jacob Simmonds, Stephanos Nicolaou, Helena J Tutill, Rachel Williams, Austen Worth, Stephen D Marks, Paul Veys, Elizabeth Whittaker, Judith Breuer
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Microbiology
Subjects:
Antiviral Agents
Cytomegalovirus Infections
herpesviruses
Next Generation Sequencing technologies
immune deficiency
Immunocompromised patients
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01317/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01317/full

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