Sinensetin Induces Autophagic Cell Death through p53-Related AMPK/mTOR Signaling in Hepatocellular Carcinoma HepG2 Cells

Sinensetin Induces Autophagic Cell Death through p53-Related AMPK/mTOR Signaling in Hepatocellular Carcinoma HepG2 Cells

Sinensetin (SIN) has been reported to exhibit anti-inflammatory and anti-cancer activity. However, the cellular and molecular mechanism by which SIN promotes hepatocellular carcinoma (HCC) cell death remains unclear. In the present study, we investigated the induction of cell death by SIN and its un...

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Bibliographic Details
Main Authors: Seong Min Kim, Sang Eun Ha, Ho Jeong Lee, Shailima Rampogu, Preethi Vetrivel, Hun Hwan Kim, Venu Venkatarame Gowda Saralamma, Keun Woo Lee, Gon Sup Kim
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Nutrients
Subjects:
sinensetin
autophagy
p53
AMPK
hepatocellular carcinoma
Online Access:https://www.mdpi.com/2072-6643/12/8/2462

Internet

https://www.mdpi.com/2072-6643/12/8/2462

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