Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function

Expression of intelectin-1 in bronchial epithelial cells of asthma is correlated with T-helper 2 (Type-2) related parameters and its function

Abstract Background Intelectin-1 (ITLN-1) is secreted by intestinal goblet cells and detectable in blood. Its expression is increased in IL-13-overexpressing mouse airways. However, its expression and function in human airways is poorly understood. Methods Distal and proximal bronchial epithelial ce...

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Bibliographic Details
Main Authors: Taiji Watanabe, Kazuyuki Chibana, Taichi Shiobara, Rinna Tei, Ryosuke Koike, Yusuke Nakamura, Ryo Arai, Yukiko Horigane, Yasuo Shimizu, Akihiro Takemasa, Takeshi Fukuda, Sally E. Wenzel, Yoshiki Ishii
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Allergy, Asthma & Clinical Immunology
Subjects:
Intelectin-1
Bronchial asthma
Bronchial epithelial cells
IL-13
Type-2 related parameters
Online Access:http://link.springer.com/article/10.1186/s13223-017-0207-8

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http://link.springer.com/article/10.1186/s13223-017-0207-8

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