CD4:CD8 Lymphocyte Ratio as a Quantitative Measure of Immunologic Health in HIV-1 Infection: Findings from an African Cohort with Prospective Data

In individuals with human immunodeficiency virus type 1 (HIV-1) infection, CD4:CD8 lymphocyte ratio is often recognized as a quantitative outcome that reflects the critical role of both CD4+ and CD8+ T-cells in HIV-1 pathogenesis or disease progression. Our work aimed to first establish the dynamics...

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Bibliographic Details
Main Authors: Jianming eTang, Xuelin eLi, Matthew A Price, Eduard J Sanders, Omu eAnzala, Etienne eKarita, Anatoli eKamali, Shabir eLakhi, Susan eAllen, Eric eHunter, Richard A Kaslow, Jill eGilmour
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Microbiology
Subjects:
HLA
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00670/full