Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry

Abstract SARS-CoV-2 spike proteins are responsible for the membrane fusion event, which allows the virus to enter the host cell and cause infection. This process starts with the binding of the spike extramembrane domain to the angiotensin-converting enzyme 2 (ACE2), a membrane receptor highly abunda...

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Bibliographic Details
Main Authors: Alessandra Luchini, Samantha Micciulla, Giacomo Corucci, Krishna Chaithanya Batchu, Andreas Santamaria, Valerie Laux, Tamim Darwish, Robert A. Russell, Michel Thepaut, Isabelle Bally, Franck Fieschi, Giovanna Fragneto
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-93996-x